Neurotrophic factors: Deciphering fly neurotrophism.

摘要

Development of a high level of motor skill performance requires practice. Interestingly, human functional MRI studies show that motor skill training can lead to decreased functional activation in the primary motor cortex (Ml), suggesting that practice increases motor system efficiency. To examine this, Picard eta!, measured functional activity and neuronalfiring in Ml of monkeys while they performed sequential reaching tasks that were designed to engage newly learnt or highly practised motor skills. Neuronal firing rates were similar in both types of tasks, but functional activation was decreased in the tasks engaging well-practised movements, indicating that practice increases the efficiency of Ml neuronal activity. ORIGINAL RESEARCH PAPER Picard