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Robot-assisted laparoscopic partial adrenalectomy: initial experience.

机译:机器人辅助的腹腔镜部分肾上腺切除术:初步经验。

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OBJECTIVES: To evaluate the feasibility of performing robot-assisted laparoscopic partial adrenalectomy (RALPA) in patients seen at the National Cancer Institute and report the results of our initial experience. METHODS: We reviewed the records of patients with adrenal masses who underwent attempted RALPA from July of 2008 until January of 2010. Demographic, perioperative, and pathologic data were collected. The functional and early oncological outcomes were examined by the need for steroid replacement and development of recurrent disease, respectively. RESULTS: Ten patients underwent a total of 13 attempted RALPAs for removal of 19 adrenal tumors. There was one open conversion with successful completion of partial adrenalectomy. Of the patients, 80% had a known hereditary syndrome predisposing them to adrenal tumors. One patient had bilateral multifocal adrenal masses with unknown germ line genetic alteration and 1 patient had a sporadic adrenal mass. Of the 19 tumors removed, 17 were pheochromocytoma and 2 were adrenal-cortical hyperplasia. Two patients underwent partial adrenalectomy on a solitary adrenal gland, with one subsequently requiring steroid replacement postoperatively. On postoperative imaging, all but one operated adrenal gland demonstrated contrast enhancement. No patient developed local recurrence at a median follow-up of 16.2 months (range, 2-29). CONCLUSIONS: RALPA appears safe and feasible in our early experience. Only 1 patient in our series required steroid replacement. Local recurrence rates are low but will require longer follow-up.
机译:目的:评估在美国国家癌症研究所(National Cancer Institute)看到的患者中进行机器人辅助腹腔镜部分肾上腺切除术(RALPA)的可行性,并报告我们的初步经验结果。方法:我们回顾了从2008年7月至2010年1月接受RALPA尝试的肾上腺肿块患者的记录。收集了人口统计学,围手术期和病理学数据。功能和早期肿瘤学结果分别通过类固醇替代和复发性疾病的发展进行了检查。结果:10例患者总共接受了13次RALPA尝试,以清除19例肾上腺肿瘤。成功完成部分肾上腺切除术后进行了一次开放式转换。在这些患者中,有80%患有已知的遗传综合征,易患肾上腺肿瘤。 1例患者双侧多灶性肾上腺肿块,种系遗传改变未知,1例患者散在肾上腺肿块。在切除的19个肿瘤中,有17个是嗜铬细胞瘤,2个是肾上腺皮质增生。两名患者在孤立的肾上腺接受了部分肾上腺切除术,其中一名患者术后需要类固醇替代。术后影像检查显示,除一个手术的肾上腺外,所有造影剂均显示对比度增强。没有患者在中位随访16.2个月(范围2-29)时出现局部复发。结论:根据我们的早期经验,RALPA似乎是安全可行的。我们系列中只有1名患者需要类固醇替代。局部复发率较低,但需要更长的随访时间。

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