目的:了解孕产妇感染弓形体(TOX)的情况.方法:采用检测血清中TOX特异性抗体的血清学方法,对338例孕产妇(其中220例为胎儿流产孕妇,118例为畸胎产妇),60例对照组(门诊健检孕妇)的血清进行了TOX-IgM和IgG抗体检测.结果:220例流产孕妇血清TOX-IgM抗体阳性33例,阳性率15.0%;IgG抗体阳性12例,阳性率5.5%(总阳性45例,阳性率20.5%).畸胎产妇118例TOX- IgM阳性15例,阳性率12.7%;IgG阳性7例,阳性率5.9%(总阳性22例,阳性率10.6%).60例对照组TOX-IgM阳性1例,阳性率1.7%.3组TOX-IgM阳性率比较分别为:孕妇组差异有非常显著性意义(X2＝48.758 P<0.001).产妇组差异有显著性意义(X2＝5.931 P<0.05).结论:TOX感染与部分孕妇流产、死胎、畸胎有关.%Objective: To understand the maternal infection toxoplasmosis ( TOX ). Method: Using se-rological methods to detect the TOX specific antibodies in serum of 338 cases of pregnant women ( including 220 cases of fetal loss pregnant women, serum of 118 cases of fetal teratogenic maternal ), 60 cases of control group ( out-patient health check pregnant women ) were detected TOX-IgM and IgG antibody. Result: 220 cases of abortion, maternal serum TOX-IgM antibody was positive in 33 cases, the positive rate was 15. 0% ; IgG antibody was positive in 12 cases, the positive rate was 5.5% ( total 45 cases positive, the positive rate of 20.5% ). Teratogenic maternal 118 cases TOX-IgM was positive in 15 cases, the positive rate was 12. 7% ; of IgG was positive in seven cases, the positive rate of 5. 9% ( total 22 cases positive, the positive rate of 10.6% ). TOX-IgM positive one case in the control group , the positive rate was 1.7%. In TOX-IgM positive rate three groups are as follows: pregnant women group difference was significant ( X = 48.758, P <0. 001 ). Maternal group difference was significant ( X2 = 5. 931, P <0. 05 ). Conclusion: TOX infection is related with the part of the miscarriage, stillbirth, birth defects.
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