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Design and analysis of micro-stirrer for thrombus dissolution

机译:血栓溶解微搅拌器的设计与分析

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Thrombus or blood clot may cause cerebral infarction and myocardial infarction if the clot can not be dissolved within several hours after it was formed. The objective of this study is to design a new structure of stirrer for thrombus dissolution. In this paper, to stir the solution with a high viscosity like blood, large amplitude was confirmed to be necessary for the stirrer by the fundamental experiment. For this purpose, shape of the stirrer and type of the actuator were changed, and force and displacement of the stirrer were analyzed. Sine waves with the resonance frequencies of the stirrer (50 V; 571 Hz) were used as the input signals. The performance of the stirrer was simulated by Finite Element Analysis (FEA) to obtain large displacement. Results showed that the amplitude at the tip of stirrer was 100 times larger than the output displacement of the PZT actuator stimulated with the resonance frequency. Concluding this paper, a new type of the micro-stirrer was designed and analyzed by FEA and it was found that the proposed stirrer had a large amplitude with a good input voltage efficiency.
机译:血栓或血凝块可能导致脑梗死和心肌梗塞如果在形成后几个小时内凝块不能溶解。本研究的目的是设计血栓溶解的搅拌器的新结构。本文用高粘度搅拌溶液,如血液,通过基本实验确认搅拌器需要大的振幅。为此目的,改变搅拌器的形状和致动器的类型,并分析搅拌器的力和位移。使用搅拌器的共振频率的正弦波(50V; 571 Hz)作为输入信号。通过有限元分析(FEA)模拟搅拌器的性能以获得大的位移。结果表明,搅拌器尖端的幅度大于用谐振频率刺激的PZT致动器的输出位移100倍。结束本文,通过FEA设计并分析了一种新型的微搅拌器,发现所提出的搅拌器具有良好的输入电压效率的大振幅。

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