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Gastric helicobacter 16 S rDNA sequences from cattle and pigs and their use for detection and typing of Helicobacter strains

机译：牛和猪的胃幽门螺杆菌16 S rDNA序列及其在幽门螺杆菌菌株检测和分型中的应用

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摘要

The present invention relates to new Helicobacter 16S rRNA or rDNA polynucleotide sequences useful for detection and typing of Helicobacter infected human and animal samples. The present invention relates more particularly to new "Candidatus Helicobacter bovis" and "Candidatus Helicobacter suis" sequences as defined in SEQ ID NO 1 and 2, sequence variants and fragments thereof. These new Helicobacter sequences allow the design of sequence specific probes and primers for detection and typing of the strains they are derived from. Diagnostic methods and kits employing such new bovine and porcine Helicobacter sequences are also disclosed.

机译：本发明涉及新的幽门螺杆菌 16S rRNA或rDNA多核苷酸序列，可用于检测和分型幽门螺杆菌感染的人和动物样品。本发明更具体地涉及如SEQ ID NO 1和2所定义的新的“ I.Candidatus” Helicobacter bovis”和“ I”“ Candidatus” Helisbacter suis”序列，其序列变体和片段。这些新的 Helicobacter 序列允许设计序列特异性的探针和引物，以检测和分型它们所衍生的菌株。还公开了使用这种新的牛和猪幽门螺杆菌序列的诊断方法和试剂盒。 展开▼

著录项

公开/公告号EP1035219A1

专利类型

公开/公告日2000-09-13

原文格式PDF

申请/专利权人 UNIVERSITEIT GENT;
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申请/专利号EP19990870035

发明设计人 QUINT WILHELMUS;DUCATELLE RICHARD;DE GROOTE DOMINIQUE;VAN DOORN LEENDERT-JAN;HAESEBROUCK FREDDY;
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申请日1999-02-25

分类号C12Q1/68;A61K31/70;

国家 EP

入库时间 2022-08-22 01:46:53

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3. Helicobacter and Wolinella species-specific detection and identification using new oligonucleotide primers directed to 16S rRNA consensus sequences [P] . 德国专利： DE19944168A1 . 2000-03-23

机译：使用针对16S rRNA共有序列的新寡核苷酸引物进行幽门螺杆菌和沃林氏菌物种特异性检测和鉴定

4. MICROBIAL TEST STRAIN OF Helicobacter pylori GKPM-Obolensk V-7215 FOR INDICATION AND IDENTIFICATION OF Helicobacter pylori IN SAMPLES OF BIOPSY MATERIALS OF GASTRIC OR DUODENAL ULCER [P] . 俄罗斯专利： RU2595422C1 . 2016-08-27

机译：幽门螺杆菌GKPM-Obolensk V-7215微生物试验菌株在胃或十二指肠溃疡活检材料样品中对幽门螺杆菌的指示和鉴定

5. composition, pharmaceutical composition, effervescent dosage form, multiple unit oral oral pharmaceutical composition, extended release pharmaceutical dosage form, enteric coated pharmaceutical dosage form, stable pharmaceutical dosage form for oral administration to mammalian subjects, method for treating diseases acid-related diseases by inhibiting gastric acid secretion, method for treating a bacterial infection caused or caused by helicobacter pylori, process for preparing a compound of formula 3, process for preparing a compound of formula 5, use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion, use of a compound of formula 1 for the preparation of a medicament for treating a bacterial infection caused or caused by helicobacter pyl or use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion [P] . BRPI0617987A2 . 2011-08-16

机译：组合物，药物组合物，泡腾剂型，多单位口服口服药物组合物，缓释药物剂型，肠溶衣药物剂型，向哺乳动物受试者口服给药的稳定药物剂型，通过抑制胃酸治疗疾病的方法酸分泌，治疗由幽门螺杆菌引起或引起的细菌感染的方法，制备式3化合物的方法，制备式5化合物的方法，式1化合物在制备用于治疗胃的药物中的用途通过抑制胃酸分泌来治疗与酸有关的疾病，将式1的化合物用于制备用于治疗由幽门螺杆菌引起或引起的细菌感染的药物，或将式1的化合物用于制备用于治疗的药物通过抑制胃酸分泌来治疗胃酸相关疾病

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