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Comparative study of the effects of Helicobacter pylori on EGFR signaling in transformed human gastric epithelial and gastric adenocarcinoma cell lines

机译：幽门螺杆菌对转化的人胃上皮细胞和胃腺癌细胞系中EGFR信号转导作用的比较研究

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作者
Settles-Reaves, Beverlyn Denise;
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作者单位

Howard University;

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授予单位 Howard University;
学科
学位 Ph.D.
年度 2007
页码 147 p.
总页数 147
原文格式 PDF
正文语种 eng
中图分类
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专利

1. Effects of Helicobacter pylori on intracellular Ca2+ signaling in normal human gastric mucous epithelial cells. [J] . Marlink KL, Bacon KD, Sheppard BC, American Journal of Physiology . 2003,第1期

机译：幽门螺杆菌对正常人胃黏膜上皮细胞内Ca2 +信号转导的影响。
2. Genome‐wide mRNA–miRNA profiling uncovers a role of the microRNA miR‐29b‐1‐5p/PHLPP1 signalling pathway in Helicobacter pylori ‐ Helicobacter pyloriHelicobacter pylori ‐ driven matrix metalloproteinase production in gastric epithelial cells [J] . Datta Chandreyee, Subuddhi Arijita, Kumar Manish, Cellular microbiology . 2018,第9期

机译：基因组 - 宽mRNA-miRNA分析揭示了MicroRNA miR-29b-1-5p / phlpp1信号通路在幽门螺杆菌中的作用 - 幽门螺杆菌 - 幽门螺杆菌 - 幽门螺杆菌幽门螺杆菌 - 驱动的基质金属蛋白酶酶生产在胃上皮细胞中

3. Helicobacter pylori-derived extracellular vesicles increased in the gastric juices of gastric adenocarcinoma patients and induced inflammation mainly via specific targeting of gastric epithelial cells [J] . Hyun-IlChoi, Jun-PyoChoi, JiwonSeo, Experimental & molecular medicine. . 2017,第5期

机译：幽门螺杆菌来源的细胞外囊泡在胃腺癌患者的胃液中增加，并主要通过特异性靶向胃上皮细胞诱导炎症

4. Effect of chronic Helicobacter pylori infection on expression of IKK-β, NF-κB, XIAP in human gastric epithelial cell line [C] . First Zhengzhou International Oncology Congress（ZIOC）- An Update on Diagnosis and Treatment of Solid Tumors, 2005 . 2005

机译：慢性幽门螺杆菌感染对人胃上皮细胞株IKK-β，NF-κB，XIAP表达的影响

5. Gastric epithelial cells act as antigen -presenting cells (APCs): Relevance to Helicobacter pylori infection [D] . Barrera Zamora, Carlos Alberto 2001

机译：胃上皮细胞充当抗原呈递细胞（APC）：与幽门螺杆菌感染的相关性

6. Helicobacter pylori-derived extracellular vesicles increased in the gastric juices of gastric adenocarcinoma patients and induced inflammation mainly via specific targeting of gastric epithelial cells [O] . Hyun-Il Choi, Jun-Pyo Choi, Jiwon Seo, 2017

机译：幽门螺杆菌来源的细胞外囊泡在胃腺癌患者的胃液中增加并主要通过特异性靶向胃上皮细胞诱发炎症

7. Vacuolating toxin from Helicobacter pylori activates cellular signaling and pepsinogen secretion in human gastric adenocarcinoma cells [O] . Chan Err-Cheng, Chen Kuei-Tian, Lin Yuh-Ling 1996

机译：幽门螺杆菌的排空毒素激活人胃腺癌细胞中的细胞信号传导和胃蛋白酶原分泌

1. 胃癌高低发区差异基因型幽门螺杆菌菌株对人胃上皮细胞系 GES-1的损伤作用 [J] . 何红梅 ,宫月华 ,袁媛 . 世界华人消化杂志 . 2005,第22期

2. CagA阳性幽门螺杆菌诱导人胃粘膜上皮细胞系(GES-1)白细胞介素-1 β分泌的细胞内信号转导途径 [J] . 李岭 ,陈卫昌 ,江家贵 . 苏州大学学报（医学版） . 2004,第006期

3. 酱香型白酒中生物活性物质抗幽门螺杆菌代谢物诱导的人胃上皮细胞炎症作用研究 [J] . 罗强 ,刘杰 ,刘志刚 . 食品与发酵科技 . 2020,第004期

4. 幽门螺杆菌诱导胃上皮细胞白细胞介素-8基因转录的信号转导机制 [J] . 李淑德 ,许国铭 ,李兆申 . 胃肠病学 . 2005,第002期

5. 幽门螺杆菌细胞空泡毒素与胃上皮细胞的表皮生长因子信号转导 [J] . 杜奕奇 ,许国铭 ,李兆申 . 微生物与感染 . 2003,第004期

6. EGFR信号通路在二氧化硅对肺上皮细胞间质转化中的作用机制 [C] . 宋文文 ,张华 ,孙少杰 . 第十三届全国劳动卫生与职业病学术会议 . 2014

7. 幽门螺杆菌在胃上皮细胞及胃腺癌细胞增殖凋亡中的作用及机制研究 [A] . 温晋锋 . 2014

1. 免疫毒素在制备治疗头颈鳞状上皮细胞癌或膀胱癌药物中的应用 [P] . 中国专利： CN100417414C . 2008.09.10

2. 用于生物制品生产的人胚肺转化细胞系 [P] . 中国专利： CN101157909B . 2012.01.04

3. Compound, process for the preparation of it, pharmaceutical formulation, use of the compound, processes to inhibit gastric acid secretion, for the treatment of inflammatory gastrointestinal diseases, and for the treatment or prophylaxis of conditions involving helicobacter pylori infection of the mucosa human gastric, and, pharmaceutical formulations for use in inhibiting gastric acid secretion, for use in the treatment of inflammatory gastrointestinal diseases, and for use in the treatment or prophylaxis of conditions involving helicobacter pylori infection of the human gastric mucosa [P] . 外国专利： BR9913103A . 2001-05-08

机译：该化合物，其制备方法，药物制剂，该化合物的使用，抑制胃酸分泌的方法，用于治疗炎性胃肠疾病以及用于治疗或预防人胃黏膜幽门螺杆菌感染的疾病的方法，以及用于抑制胃酸分泌，用于治疗炎性胃肠疾病以及用于治疗或预防涉及人胃粘膜的幽门螺杆菌感染的疾病的药物制剂

4. composition, pharmaceutical composition, effervescent dosage form, multiple unit oral oral pharmaceutical composition, extended release pharmaceutical dosage form, enteric coated pharmaceutical dosage form, stable pharmaceutical dosage form for oral administration to mammalian subjects, method for treating diseases acid-related diseases by inhibiting gastric acid secretion, method for treating a bacterial infection caused or caused by helicobacter pylori, process for preparing a compound of formula 3, process for preparing a compound of formula 5, use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion, use of a compound of formula 1 for the preparation of a medicament for treating a bacterial infection caused or caused by helicobacter pyl or use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion [P] . 外国专利： BRPI0617987A2 . 2011-08-16

机译：组合物，药物组合物，泡腾剂型，多单位口服口服药物组合物，缓释药物剂型，肠溶衣药物剂型，向哺乳动物受试者口服给药的稳定药物剂型，通过抑制胃酸治疗疾病的方法酸分泌，治疗由幽门螺杆菌引起或引起的细菌感染的方法，制备式3化合物的方法，制备式5化合物的方法，式1化合物在制备用于治疗胃的药物中的用途通过抑制胃酸分泌来治疗与酸有关的疾病，将式1的化合物用于制备用于治疗由幽门螺杆菌引起或引起的细菌感染的药物，或将式1的化合物用于制备用于治疗的药物通过抑制胃酸分泌来治疗胃酸相关疾病

5. Compound, process for preparing it, pharmaceutical formulation, use of a compound, and methods for inhibiting gastric acid secretion, for treating inflammatory gastrointestinal diseases, and for treating or prophylaxis of conditions involving human gastric mucosa helicobacter pylori infection [P] . 外国专利： BR0211846A . 2004-09-08

机译：该化合物，其制备方法，药物制剂，该化合物的用途以及抑制胃酸分泌，治疗炎性胃肠疾病以及治疗或预防涉及人胃粘膜幽门螺杆菌感染的疾病的方法

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Comparative study of the effects of Helicobacter pylori on EGFR signaling in transformed human gastric epithelial and gastric adenocarcinoma cell lines

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