首页>
外国专利>
ORAL PREPARATIONS CONTAINING FORSKOLIN DERIVATIVES AND PROCESS FOR PRODUCING MEDICINAL PREPARATIONS
ORAL PREPARATIONS CONTAINING FORSKOLIN DERIVATIVES AND PROCESS FOR PRODUCING MEDICINAL PREPARATIONS
展开▼
机译:包含佛斯考林衍生物的口服制剂以及制备药物制剂的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A salt of a forskolin derivative represented by the following general structural formula (1), such as colforsin dapropate hydrochloride [hydrochloride of 6-(3-dimethylaminopropionyl) forskolin] And an alkali metal halide, which are excellent in storage stability.;In the above formula, ROneRepresents hydrogen; R4Represents a vinyl group; R2And R3One of;-CO (CH2) mNR5R6(Where R5And R6And m represents an integer of 1 to 5, and the other represents hydrogen or-CO (CH2)nX where X is hydrogen or-NR7R8(Where R7And R8Each represent a lower alkyl group and the like, and n is an integer of 1 to 5].
展开▼
机译:由下列通式(1)表示的福斯高林衍生物的盐,例如考尔福斯丙酸酯盐酸盐[6-(3-二甲基氨基丙酰基)福斯高林的盐酸盐]和碱金属卤化物,其储存稳定性优异。上式中,R One Sup>代表氢; R 4 Sup>表示乙烯基; R 2 Sup>和R 3 Sup>其中之一; -CO(CH 2 Sub>)mNR 5 Sup> R 6 < / Sup>(其中R 5 Sup>和R 6 Sup> And m表示1到5的整数,另一个表示氢或-CO(CH 2 Sub>) n Sub> X其中X是氢或-NR 7 Sup> R 8 Sup>(其中R 7 Sup> And R < Sup> 8 Sup>分别表示低级烷基等,n为1〜5的整数。
展开▼