Trypsin substrate, a diagnostic device, and use in assay for urinary trypsin inhibitor

摘要

A compound of the formula (I) CHEM (I) wherein R1 is a protecting group for N alpha , R2 is a protecting group for NG, and R3 is aryl, and wherein the compound of formula (I) is a trypsin substrate such that trypsin cleaves the O-C single bond, which liberates R3-OH; a diagnostic device comprising same; a method for preparing the diagnostic device; and a method of using the diagnostic device to detect levels of urinary trypsin inhibitor in a biological sample; and a diagnostic kit for detecting levels of urinary trypsin inhibitor in a biological sample.