首页> 外国专利> Process of obtainment of racemic cetamine enantiomers; process of obtainment of pharmaceutically acceptable salts from racemic cetamine enantiomes and use of pharmaceutically acceptable salts obtained by means of said mentioned process

Process of obtainment of racemic cetamine enantiomers; process of obtainment of pharmaceutically acceptable salts from racemic cetamine enantiomes and use of pharmaceutically acceptable salts obtained by means of said mentioned process

机译:外消旋鲸蜡胺对映体的获得过程;消旋鲸蜡胺对映体获得可药用盐的方法以及通过所述方法获得的可药用盐的用途

摘要

The present invention describes a new process for obtainment of the cetamine enantiomers, from the racemic cetamine resolutions with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers. The resolution agent is employed in special concentration conditions, which provides stability, reproducibility and high enantiomeric purity to the precipitated diasteromer salt, making feasible the industrial production of the S-cetamine and its pharmaceutically acceptable salts.
机译:本发明描述了在手性拆分剂的帮助下从外消旋的鲸蜡胺拆分物中获得鲸蜡胺对映异构体的新方法,其提供了其对映异构体的选择性结晶。拆分剂在特殊的浓度条件下使用,可为沉淀的非对映体盐提供稳定性,可重复性和高对映体纯度,使S-鲸蜡胺及其药学上可接受的盐的工业生产成为可能。

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