PEPTIDE-MIMETICS AND USE THEREOF AS INHIBITORS OF THE 20S PROTEASOME, 26S PROTEASOME AND THE IMMUNOPROTEASOME

摘要

The invention relates to mimetic peptide compounds, to the synthesis and usethereof for inhibiting proteasomes and inducing apoptosis in tumoral cells.Pharmaceutical compositions containing said compounds and the use of saidcompounds for treating diseases, in particular cancer and neurogenerativediseases are also disclosed.