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Peptide mimetics and their use as inhibitors of the 20S proteasome, 26S proteasome and immune proteasome
Peptide mimetics and their use as inhibitors of the 20S proteasome, 26S proteasome and immune proteasome
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机译:肽模拟物及其作为20S蛋白酶体,26S蛋白酶体和免疫蛋白酶体的抑制剂的用途
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摘要
The present invention relates to peptide-mimetic compounds, the synthesis and use thereof fort he inhibition of proteasomes and the induction of apoptosis in tumor cells. The present invention furthermore relates to pharmaceutical compositions comprising the compounds and the use of the compounds for a treatment of diseases, in particular cancer and neurodegenerative diseases.
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