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CRYPTOTIS PARVA SCREENING MODEL FOR ANTIEMETIC POTENTIAL

机译：隐性的隐性隐性筛选模型

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摘要

The present invention provides for anrelate to an animal model for characterizing emesis, and for screening and characterizing emetic and antiemetic agents. In several embodiments, the Least Shrew, Cryptotis parva, provides a specific and rapid behavioral animal model to screen concomitantly both the CNS penetration and the antiemetic potential of antiemetic agents to relieve, for example, chemotherapy-induced emesis.

机译：本发明提供了用于表征呕吐，用于筛选和表征催吐剂和止吐剂的动物模型。在几个实施方案中，最小Sh，隐孢子虫提供了一种特定且快速的行为动物模型，以同时筛选CNS渗透和止吐药的止吐潜力，以缓解例如化疗引起的呕吐。。 展开▼

著录项

公开/公告号US2011093959A1

专利类型

公开/公告日2011-04-21

原文格式PDF

申请/专利权人 NISSAR A. DARMANI;
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申请/专利号US20090865597

发明设计人 NISSAR A. DARMANI;
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申请日2009-01-30

分类号A01K67/00;C07D407/04;

国家 US

入库时间 2022-08-21 18:14:04

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