THE CRYPTOTIS PARVA SCREENING MODEL FOR ANTIEMETIC POTENTIAL

摘要

The present invention provides for anrelate to an animal model for characterizing emesis, and for screening and characterizing emetic and antiemetic agents. In several embodiments, the Least Shrew, Crγptotis parva, provides a specific and rapid behavioral animal model to screen concomitantly both the CNS penetration and the antiemetic potential of antiemetic agents to relieve, for example, chemotherapy-induced emesis.