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BIOLOGICAL METHODS OF ANALYSIS FOR QUALITY CONTROL OF NUTRICE WOMEN AND MEDICINES
BIOLOGICAL METHODS OF ANALYSIS FOR QUALITY CONTROL OF NUTRICE WOMEN AND MEDICINES
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机译:营养妇女和药品质量控制的生物学分析方法
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摘要
1. A method for detecting or determining whether a substance has one or more useful biological, nutraceutical or therapeutic properties, which includes: performing expression in a sample of a first biological marker to suppress translation initiation from the first mRNA in the presence of a test substance: determining the expression level of said first biological marker in the specified sample; comparing the expression level of said first biological marker with a control expression level, wherein the expression level of said first biological marker exceeding a control expression level indicates that the test substance is a substance that has one or more favorable biological, nutraceutical or therapeutic properties. 2. The method of claim 1, wherein comparing the expression level of said first biological marker with a control expression level comprises: expressing in a sample a second biological marker to suppress translation initiation from a second mRNA in the presence of a control substance; determining an expression level of a second biological marker in a sample; comparing the expression level of said first biological marker with the expression level of said second biological marker. 3. The method according to any one of claims 1 or 2, wherein the first mRNA and the second mRNA have at least two open reading frames as part of their 5 'untranslated regions, and wherein the 5' untranslated region of the first mRNA is functionally connected to the coding region that encodes the specified first biological marker suppress
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