THIOL-ENE CLICK CHEMISTRY FOR DRUG CONJUGATES

摘要

The present invention relates to linker molecules that readily conjugate cellular recognition ligand at one end and drug payload at the other, and are useful in treating or preventing cancer, an autoimmune disease, an inflammatory condition, a central nervous system disorder or an infection. The Invention includes linker molecules, Linker - Drug compounds, and Ligand - Linker - Drug conjugates.