B. Transformed T cells and T cell receptors for anticancer immunology

摘要

T (TCR) cell receptors bind to tumor antigen (TAA) to metastasize to cancer cells.T cells representing these cellsProduction and treatment of cancer Especially,This note deals with TCR and its variability and peptide binding to HLA molecules of class I or II.For example, the amino acid sequence of MAG-003 is Kvlehvv (SEQ ID n 1). It also involves peptides.Protein.Nucleic acid and cells for immunotherapy. Especially,This description is related to immunotherapy for cancer. It also involves epithelioma of T-cell peptides associated with tumors.Individually or in combination with other cancer-related peptides may play a role.For instanceAs an active drug component in vaccine components, it can stimulate anti-tumor immune response or pre-stimulate living T cells and transfer them to patients. Peptides that bind to molecules in larger histocompatibility complexes.Or similar peptideThey may also be targets of antibodies.Receptors of T-soluble cells and other binding molecules.