首页> 外国专利> METHOD FOR PREDICTING A COMPLICATED COURSE OF THE POSTOPERATIVE PERIOD IN PATIENTS WITH ISCHEMIC HEART DISEASE WITH A REDUCED CONTRACTIVE HEART FUNCTION AFTER OPEN HEART OPERATION

METHOD FOR PREDICTING A COMPLICATED COURSE OF THE POSTOPERATIVE PERIOD IN PATIENTS WITH ISCHEMIC HEART DISEASE WITH A REDUCED CONTRACTIVE HEART FUNCTION AFTER OPEN HEART OPERATION

机译:开胸后心脏功能降低的预后预测缺血性心脏病患者术后并发症的方法

摘要

The invention relates to medicine, namely to cardiac surgery, laboratory diagnostics. In accordance with the invention, a method for predicting a complicated course of the postoperative period in patients with coronary heart disease with reduced contractile heart function after open heart surgery is described, which consists in the fact that the patient undergoes an echocardiographic study in the preoperative period, in which they confirm the presence of a reduced contractility of the heart and determine the severity of functional ischemic mitral insufficiency, then assess the level in cr the ovaries of the sST2 myocardial fibrosis biomarker, compare it with a reference threshold value and at a sST2 level of less than 45 ng / ml establish a low risk of complicated postoperative course, and at an sST2 level of more than 45 ng / ml, a high risk of developing low cardiac output syndrome in postoperative period after open heart surgery. The technical result achieved by the invention is to improve the accuracy, reliability and quality of the prognosis of the complicated course of the postoperative period in patients with coronary heart disease with reduced contractile heart function after open heart surgery.
机译:本发明涉及医学,即心脏手术,实验室诊断。根据本发明,描述了一种用于预测心脏直视手术后收缩性心脏功能降低的冠心病患者的术后复杂病程的方法,该方法在于患者在术前进行了超声心动图研究。在此期间,他们确认存在心脏收缩力降低并确定功能性缺血性二尖瓣关闭不全的严重程度,然后评估sST2心肌纤维化生物标志物卵巢水平,将其与参考阈值进行比较,并在sST2水平低于45 ng / ml会降低术后复杂病程的风险,而sST2水平高于45 ng / ml会导致在心脏直视手术后的术后出现低心输出量综合征的高风险。本发明的技术成果是提高了心脏直视手术后收缩性心功能降低的冠心病患者术后复杂病程预后的准确性,可靠性和质量。

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