Composition for promoting skeletal muscle activity via induction of mitochondrial biogenesis comprising of azelaic acid as an active ingredient

摘要

The present invention relates to a composition for promoting the synthesis of mitochondria comprising azelaic acid as an active ingredient, wherein the azelaic acid is a compound mainly contained in natural products such as cereals and cranberries, such as wheat, oats, barley, sorghum and rye. In addition, it was confirmed that there is an activity that induces autophagy of mitochondria and mitochondrial DNA synthesis in the cell and ultimately increases the density of mitochondria, and fails to regulate mitochondrial homeostasis such as mitochondrial activity or decrease in the number of mitochondria. It can be used for the treatment of diseases related to mitochondrial dysfunction according to. In addition, by using the activity can be provided for the use for the strengthening of muscle function and preventing muscle aging, the azelaic acid according to the present invention for the treatment of diseases related to mitochondrial deterioration, food for strengthening muscle function, or preventing muscle aging It can be usefully used for materials, pharmaceutical compositions, and health functional foods.