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首页> 外文期刊>Osteoarthritis and cartilage >Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS)
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Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS)

机译:膝关节外科软骨修复的全关节MRI评估:软骨修复骨关节炎膝关节评分(CROAKS)

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Objective: To develop amagnetic resonance imaging (MRI) scoring system for follow-up of knee cartilage repair procedures integrating assessment of the repair site and the whole joint called Cartilage Repair OsteoArthritis Knee Score (CROAKS), and to assess its reliability. Design: MRI examinations of 20 patients that had undergone matrix-associated autologous chondrocyte transplantation (MACT) of the knee 12 months before were semi-quantitatively assessed for the repair site using features of the magnetic resonance observation of cartilage repair tissue (MOCART) system and for the whole joint based on experiences with the MRI Osteoarthritis Knee Score (MOAKS) instrument. Intra- and inter-observer reliability was calculated using weighted (w) kappa statistics for plates (medial/lateral tibia, medial/lateral femur, trochlea, patella), compartments (medial tibio-femoral, lateral tibio-femoral, patello-femoral) and the whole joint. For certain features with low prevalence the overall percent agreement was calculated in addition. Results: For cartilage, reliability on a plate level ranged between 0.48 (lateral femur) and 1.00 (medial femur). BML assessment showed comparable results ranging on a plate level between 0.46 and 1.00 with overall percent agreement between 83.3% and 100%. Meniscal morphology assessment ranged between 0.62 and 0.94. For repair site assessment reliability ranged from 0.41 (signal intensity inter-observer) to 1.00 (several features). Overall percent agreement was above 80% for 17 of 22 features assessed (intra- and inter-observer results combined). Conclusions: Combined scoring of the repair site and whole joint assessment for common osteoarthritis features using CROAKS, which is based on experience with two established semi-quantitative scoring tools, is feasible and may be performed with good to excellent reliability.
机译:目的:开发一种磁共振成像(MRI)评分系统,用于对膝关节软骨修复程序进行跟踪,并结合对修复部位和整个关节的评估,称为软骨修复骨关节炎膝关节评分(CROAKS),并评估其可靠性。设计:利用软骨修复组织(MOCART)系统的磁共振观察特征和20个月前进行膝关节基质相关自体软骨细胞移植(MACT)的20例患者的MRI检查,对其修复部位进行半定量评估。基于MRI骨关节炎膝关节评分(MOAKS)仪器的经验来评估整个关节。观察者间和观察者间的可靠性是通过加权(w)kappa统计量来计算的:钢板(内侧/外侧胫骨,内侧/外侧股骨,滑车,骨),车厢(内侧胫股,外侧胫股、,骨)和整个关节。对于某些患病率较低的特征,还计算了总体一致性百分比。结果:对于软骨,板水平的可靠性介于0.48(外侧股骨)和1.00(内侧股骨)之间。 BML评估显示可比较的结果在0.46至1.00的塔板级范围内,总体百分比一致性在83.3%至100%之间。半月板形态评估范围为0.62至0.94。对于维修现场评估,可靠性的范围从0.41(观察者之间的信号强度)到1.00(多个功能)。评估的22项功能中有17项的总体一致性百分比高于80%(观察者内部和观察者之间的结果总计)。结论:基于两个已建立的半定量评分工具的经验,结合CROAKS对骨关节炎常见特征进行的修复部位评分和全关节评估,是可行的,并且可能具有良好的可靠性。

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