The IncRNA Pnky in the Brain

摘要

Long noncoding RNAs (IncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract-binding protein 1 (PTBP1).