Age and Gender Modulation of the Long QT Syndrome Phenotype

摘要

This article reviews the manner in which age and gender affect electrocardiographic measurements of repolarization and therefore the QT interval. The authors detail the effects of age and gender on clinical outcomes in long QT syndrome and review how these modulations drive treatment recommendations. They also discuss basic research that has recently begun to shed light on these clinical phenomena and may give insight into potential future treatments.