Comments on ' Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize'

摘要

We are contacting you to bring to your editorial attention about the recently published paper by Seralini et al. (2012) at the Journal of Food and Chemical Toxicology where you are an Editor-in-chief.With the explanation below, we would like to call for the journal's immediate action on the paper. We are not going to repeat all the well justified responses of colleagues around the world on this paper, (Science Media Centre, 2012; Ashley Ng, 2012; Academic Review, 2012; Huffingtonpost, 2012; CNSR, 2012) however, presented here below are the three points that may constitute a sufficient ground to request an editorial retraction of the paper.The rat strain used in the study has been known to be prone to cancer during their lifetime, especially when they get aged. In a study by Nakazawa and co-workers consisting of 2 groups of 120 males and 120 females Sprague-Dawley rats, the same strain that were used in the study of Seralini et al., it was evidence that, under ad libitum, the rat developed tumors with an incidence ranges from 70% to 95.8% during their lifetime of 89-105 weeks (Nakazawa et al., 2001). Thus, the use of this rat strain had made the comparison of tumor occurrence in aged rats difficult and unclear.