Efficacy and safety of weekly leflunomide for the treatment of early rheumatoid arthritis: a randomized, multi-center study

Ren Li-Min; Li Ru; Chen Li-Na; Zhu Ping; Gu Fei; Sun Ling-Yun; Zhao Jin-Xia; Liu Xiang-Yuan; Guo Jia-Long; Bi Li-Qi; Hao Yan-Jie; Zhang Zhuo-Li; Mei Yi-Fang; Zhang Zhi-Yi; Liu Hua-Xiang; Li Xing-Fu; Luo Yan; Fang Yong-Fei; Li Zhan-Guo; Su Yin

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Efficacy and safety of weekly leflunomide for the treatment of early rheumatoid arthritis: a randomized, multi-center study

机译：来氟米特每周治疗早期类风湿关节炎的疗效和安全性：一项随机，多中心研究

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Aim: The aim of this study was to determine the efficacy and safety of a weekly dose of leflunomide (50 mg/week) in early rheumatoid arthritis patients with mild or moderate disease activity.

机译：目的：本研究的目的是确定每周一次来氟米特的剂量（50 mg /周）在患有轻度或中度疾病活动的早期类风湿关节炎患者中的疗效和安全性。

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来源
《International journal of rheumatic diseases》 |2016年第7期|共7页
作者
Ren Li-Min; Li Ru; Chen Li-Na; Zhu Ping; Gu Fei; Sun Ling-Yun; Zhao Jin-Xia; Liu Xiang-Yuan; Guo Jia-Long; Bi Li-Qi; Hao Yan-Jie; Zhang Zhuo-Li; Mei Yi-Fang; Zhang Zhi-Yi; Liu Hua-Xiang; Li Xing-Fu; Luo Yan; Fang Yong-Fei; Li Zhan-Guo; Su Yin;
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正文语种 eng
中图分类全身性疾病;
关键词
leflunomide; rheumatoid arthritis; weekly regimen;

机译：来氟米特;类风湿关节炎;每周治疗;

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专利

1. Efficacy and safety of weekly leflunomide for the treatment of early rheumatoid arthritis: a randomized, multi-center study [J] . Ren Li-Min, Li Ru, Chen Li-Na, International journal of rheumatic diseases . 2016,第7期

机译：来氟米特每周治疗早期类风湿关节炎的疗效和安全性：一项随机，多中心研究
2. Efficacy and safety of leflunomide 10 mg versus 20 mg once daily in patients with active rheumatoid arthritis: multinational double-blind, randomized trial. [J] . Poor G, Strand V Rheumatology . 2004,第6期

机译：活动性类风湿性关节炎患者中来氟米特10 mg和每日20 mg来氟米特的疗效和安全性：跨国双盲，随机试验。
3. Comparative efficacy and tolerability of monotherapy with leflunomide or tacrolimus for the treatment of rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials [J] . Bae Sang-Cheol, Lee Young Ho Clinical rheumatology . 2018,第2期

机译：单疗法与左旋瘤或躯干植物治疗类风湿性关节炎的比较疗效和耐受性：随机对照试验的贝叶斯网络荟萃分析
4. Inflammatory gene profile in early rheumatoid arthritis and odulation by leflunomide and prednisone treatment [C] . Mgurizio Cutolo, Barbara Villaggio, Carmen Pizzorni, International Conference on the Neuroendocrine Immune Basis of the Rheumatic Diseases . 2010

机译：早期类风湿性关节炎和偏血清血清血清炎和泼尼松治疗的炎症基因谱
5. Comparison of the Therapeutic Efficacy of Rheumatoid Arthritis Treatments [D] . Davis, Kacy. 2021

机译：类风湿性关节炎治疗治疗疗效的比较
6. The Efficacy and Safety of the Combination of Total Glucosides of Peony and Leflunomide for the Treatment of Rheumatoid Arthritis: A Systemic Review and Meta-Analysis [O] . Zhitao Feng, Juan Xu, Guochao He, 2016

机译：牡丹与来氟米特总苷在类风湿关节炎治疗中的疗效和安全性：系统评价和荟萃分析
7. Treatment with leflunomide slows radiographic progression of rheumatoid arthritis: Results from three randomized controlled trials of leflunomide in patients with active rheumatoid arthritis [O] . John T. Sharp, Vibeke Strand, Hoi Leung, 2000

机译：用leflunomide治疗减缓了类风湿性关节炎的放射线进展：活性类风湿性关节炎患者的三种随机对照试验的结果来自leflunomide的三种随机对照试验

Efficacy and safety of weekly leflunomide for the treatment of early rheumatoid arthritis: a randomized, multi-center study

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