Clinical factors indicating the presence of pyogenic liver abscess in community-acquired Klebsiella pneumoniae bacteremia.

摘要

Klebsiella pneumoniae is a leading cause of pyogenic Liver abscess (PLA) in some Asian countries, where one of the most common sources of K. pneumoniae bacteremia is PLA. PLA presents a diagnostic challenge, because half of all patients show no specific symptoms or signs that direct attention to the liver. This study was conducted to identify clinical and Laboratory factors indicating the early diagnosis of PLA in community-acquired K. pneumoniae bacteremia. Patients at three hospitals in Korea, diagnosed with K. pneumoniae bacteremia between January 2001 and December 2004, were retrospectively reviewed with regard to demographic, clinical, and Laboratory data. Healthcare-associated and nosocomial cases were excluded because K. pneumoniae bacteremia associated PLA is usually community-acquired. Only community-acquired cases in adults who had undergone abdominal ultrasonography (US) or computed tomography (CT) were included. The severity of acute illness was assessed at the time of initial bacteremia byusing the simplified acute physiology score (SAPS) II.