Synthesis of Some Benzimidazolyl Chalcones

摘要

Some benzimidazolyl chalcones have been synthesized by condensation of 2-acetyl benzimidazole(3)with aromatic aldehydes in presence of aqueous KOH by microwave irradiation technique.Benzimidazoles constitute an important group of heterocyclic compounds having a wide spectrum of biological activities.2-Substituted benzimidazole derivatives have been found to be biologically most potent.Chalcones are the natural biocides and are well known intermediates in the synthesis of heterocyclic compounds exhibiting various biological activities.Introduction of heterocyclic nucleus in the chalcone system has been reported to enhance the biological activities.