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Prospects of control and eradication of capripox from the Indian subcontinent: A perspective.

机译:从印度次大陆控制和消除己内酰胺的前景:一个角度。

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摘要

Sheeppox and goatpox, two endemic capripox infections in India, pose a significant economic threat to small ruminant productivity in the subcontinent. Vaccination of all susceptible sheep and goats is the feasible and sustainable means of control. Availability of effective live attenuated vaccines that are inherently thermostable and development of improved diagnostics provide the opportunities to initiate effective control measures for capripox. All animals older than 4months can be vaccinated with the current homologous vaccines using a single vaccination by intradermal or subcutaneous routes. The success of the control program needs to be monitored by active surveillance particularly for the presence of virus, as sero-monitoring does not enable the differentiation of infection and vaccination. And also the sero-conversion following capripox vaccination is not detectable enough by the available tools. Sustained control efforts call for socio-economic and political stability, adequate infrastructure and logistic support to store and transport vaccines for reaching out vaccines to the remote end users. Availability of veterinary services, improved extension services for increased awareness among farmers, contribute significantly to the control campaigns. Poor vaccination coverage and in-adequate infrastructure in major parts of the country are some of the major elements that come in the way of effective implementation of building herd immunity through immunization.
机译:羊痘和山羊痘是印度的两种地方性Capripox感染,对次大陆的小反刍动物生产力构成了重大经济威胁。对所有易感绵羊和山羊进行疫苗接种是可行且可持续的控制手段。有效的减毒活疫苗具有固有的热稳定性,改进的诊断方法的开发提供了启动对Capripox采取有效控制措施的机会。可以通过皮内或皮下途径单次接种所有大于4个月大的动物的当前同源疫苗。需要通过主动监视来监视控制程序的成功,尤其是对于病毒的存在,因为血清监视不能区分感染和疫苗。而且,可用的工具也无法检测出Capripox疫苗接种后的血清转化。持续的控制工作要求社会经济和政治稳定,适当的基础设施和后勤支持以存储和运输疫苗,以便将疫苗提供给偏远的最终用户。兽医服务的提供,改进的推广服务以提高农民的认识,为控制运动做出了重要贡献。该国主要地区的疫苗接种覆盖率差和基础设施不足是有效实施通过免疫建立畜群免疫的主要因素。

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