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机译:活性位点替代A82w通过旋转松弛核磁共振研究改善了细胞色素P450 BM3突变体的类固醇羟基的区域选择性
LACDR/Division of Molecular Toxicology Department of Pharmacochemistry VU University Amsterdam De Boelelaan 1083 1081 HV Amsterdam The Netherlands;
Institute for Molecules and Materials Department of Biophysical Chemistry Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands;
LACDR/Division of Molecular Toxicology Department of Pharmacochemistry VU University Amsterdam De Boelelaan 1083 1081 HV Amsterdam The Netherlands;
Institute for Molecules and Materials Department of Biophysical Chemistry Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands;
Institute for Molecules and Materials Department of Biophysical Chemistry Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands;
MSD Merck Research Laboratories Medicinal Chemistry Oss Molenstraat 110 5342 CC Oss The Netherlands;
LACDR/Division of Molecular Toxicology Department of Pharmacochemistry VU University Amsterdam De Boelelaan 1083 1081 HV Amsterdam The Netherlands;
Institute for Molecules and Materials Department of Biophysical Chemistry Radboud University Nijmegen Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands;
LACDR/Division of Molecular Toxicology Department of Pharmacochemistry VU University Amsterdam De Boelelaan 1083 1081 HV Amsterdam The Netherlands;
Substitution; Mutants; Relaxation;
机译:活性位点替代A82w通过旋转松弛核磁共振研究改善了细胞色素P450 BM3突变体的类固醇羟基的区域选择性
机译:铜绿假单胞菌细胞色素C-551和欧洲亚硝化单胞菌细胞色素C-552衍生的一系列铁低自旋细胞色素C突变体中配体场各向异性的调节:核磁共振和电子顺磁共振研究
机译:在黄素细胞色素P450 BM3中不利于谷氨酸-血红素酯键的形成:表征P450 BM3的血红素位点的谷氨酸替代突变体
机译:通过主动站点工程控制CYP152A1(P450BSP)的脂肪酸羟化反应区域选择性
机译:第一部分。酵母中细胞色素C过氧化物酶的磁性圆二色性研究:通过与辣根过氧化物酶和肌红蛋白的比较,研究了活性部位血红素配位域。第二部分检查肌红蛋白(H93G),细胞色素c过氧化物酶(H175G)和血红素加氧酶(H25A)的空腔突变体的血红素活性位点配位结构,以及H17C / D235L双突变体中硫醇盐连接的细胞色素c过氧化物酶的结构研究。
机译:同源性细胞色素P450-2C11中类固醇分子的16α-羟基化和区域选择性结合模式的研究
机译:分析人类细胞色素P450 3A4的协同作用:定点突变体的构建和表征,该突变体显示双曲线甾体羟基化动力学
机译:顺磁弛豫试剂对15N自旋弛豫的影响及Gd(dpm)3作为氮-15核磁共振自旋标记的应用