Imidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer’s Disease

摘要

According to Alzheimer’s Disease International, there are nearly 36 million Alzheimer’s patients worldwide. As the global population ages, the number of patients impacted by this progressive neurodegenerative disease is expected to increase substantially. Clinical manifestations of this disease include cognitive decline, disorientation, language impairment, and permanent memory loss. In the ?nal stages of Alzheimer’s disease, patients are often totally dependent on custodial care and severely cognitively impaired.