Multicomponent One‐pot Synthesis of Oxadiazole Included Pyranopyrazoles as Promising Antioxidant Agents

摘要

> Oxadiazole‐fused combinations are of great concern for the novelty of effective therapeutic agents. In this context, a series of oxadiazole included pyranopyrazoles were prepared under eco‐friendly synthetic way by using montmorillonite k10 as a catalyst. All the final outcomes were formed with good yields. Further, compounds screened for their antioxidant assay. Most of the compounds revealed promising activity. Among all outcomes, electron rich‐substituted compounds at para position demonstrated higher antioxidant activity than their corresponding ortho ‐substituted compounds. All belongings concluded that this eco‐friendly path is preferable to prepare therapeutic compounds. Further, biotic results established that all these biologically active compounds fit for supplementary to develop exogenous antioxidant drugs.