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首页> 外文期刊>Magnetic resonance imaging: An International journal of basic research and clinical applications >Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems
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Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems

机译:12个小动物MRI系统中纵向松弛率的可重复性和再现性

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摘要

Background: Many translational MR biomarkers derive from measurements of the water proton longitudinal relaxation rate R-1, but evidence for between-site reproducibility of R-1 in small-animal MRI is lacking.
机译:背景:许多平移MR生物标志物源于水质子纵向松弛率R-1的测量,但缺乏r-1的现场再现性的证据。

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  • 作者单位

    Bioxydyn Ltd Manchester Sci Pk Rutherford House Pencroft Way Manchester M15 6SZ Lancs England;

    Merck &

    Co Inc West Point PA USA;

    Antaros Med BioVenture Hub S-43183 Molndal Sweden;

    Sanofi Aventis Deutschland GmbH R&

    D TIM Bioimaging Germany Ind Pk Hochst D-65926 Frankfurt Germany;

    Bayer AG Res &

    Dev Pharmaceut MR &

    CT Contrast Media Res Mullerstr 178 D-13353 Berlin Germany;

    In Vivo Bioimaging UK RD Platform Technol &

    Sci GSK Med Res Ctr Gunnels Wood Rd Stevenage SG1 2NY Herts England;

    Lund Univ BioImaging Ctr Klin Gatan 32 SE-22242 Lund Sweden;

    Bayer AG Res &

    Dev Pharmaceut MR &

    CT Contrast Media Res Mullerstr 178 D-13353 Berlin Germany;

    In Vivo Bioimaging UK RD Platform Technol &

    Sci GSK Med Res Ctr Gunnels Wood Rd Stevenage SG1 2NY Herts England;

    Sanofi Aventis Deutschland GmbH R&

    D TIM Bioimaging Germany Ind Pk Hochst D-65926 Frankfurt Germany;

    Sanofi Aventis Deutschland GmbH R&

    D TIM Bioimaging Germany Ind Pk Hochst D-65926 Frankfurt Germany;

    Bruker BioSpin MRI GmbH Rudolf Plank Str 23 D-76275 Ettlingen Germany;

    Univ Manchester Ctr Imaging Sci Div Informat Imaging &

    Data Sci Manchester Acad Hlth Sci Ctr Sch Hlth Sci Fac Bio Manchester M13 9PL Lancs England;

    Abbvie iSAT Discovery 1 North Waukegan Rd N Chicago IL 60064 USA;

    Lund Univ Skane Univ Hosp Dept Translat Sci Med Radiat Phys SE-20502 Malmo Sweden;

    Univ Manchester Manchester Acad Hlth Sci Ctr Div Canc Sci Sch Med Sci Fac Biol Med &

    Hlth Manchester M20 4BX Lancs England;

    Lund Univ Skane Univ Hosp Dept Translat Sci Med Radiat Phys SE-20502 Malmo Sweden;

    In Vivo Bioimaging UK RD Platform Technol &

    Sci GSK Med Res Ctr Gunnels Wood Rd Stevenage SG1 2NY Herts England;

    Univ Leeds Leeds Inst Cardiovasc &

    Metab Med Leeds LS2 9JT W Yorkshire England;

    Univ Leeds Leeds Imaging Biomarkers Grp Dept Biomed Imaging Sci LIGHT Labs Clarendon Way Leeds LS2 9JT W Yorkshire England;

    Sanofi Aventis Deutschland GmbH R&

    D TIM Bioimaging Germany Ind Pk Hochst D-65926 Frankfurt Germany;

    Bruker BioSpin MRI GmbH Rudolf Plank Str 23 D-76275 Ettlingen Germany;

    Univ Leeds Leeds Imaging Biomarkers Grp Dept Biomed Imaging Sci LIGHT Labs Clarendon Way Leeds LS2 9JT W Yorkshire England;

    Univ Leeds Leeds Inst Cardiovasc &

    Metab Med Leeds LS2 9JT W Yorkshire England;

    Radboud Univ Nijmegen Med Ctr Radiol 766 POB 9101 NL-6500 HB Nijmegen Netherlands;

    Abbvie iSAT Discovery 1 North Waukegan Rd N Chicago IL 60064 USA;

    Bayer AG Res &

    Dev Pharmaceut MR &

    CT Contrast Media Res Mullerstr 178 D-13353 Berlin Germany;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 磁性弛豫及共振现象;
  • 关键词

    MRI; Hardware stability; Biomarker; Relaxation time; Phantom; Reproducibility; Error propagation;

    机译:MRI;硬件稳定性;生物标志物;放松时间;幻影;再现性;错误传播;

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