A rare case of coexistence of allergic bronchopulmonary aspergillosis (ABPA) and active pulmonary tuberculosis- Role of CBNAAT in ABPA evaluation

摘要

Allergic bronchopulmonary aspergillosis (ABPA) first described by Hinson et al in 1952 is an immune-mediated inflammatory disease caused by hypersensitivity to Aspergillus fumigates that occurs predominantly in patients with underlying chronic airway disorders like bronchial asthma & cystic fibrosis [1,2]. In India pulmonary tuberculosis (PTB) is one of the most common chronic pulmonary infections. Among tubercular patients most of the reported cases of ABPA are among previously treated patients [3] and the others are cases of ABPA misdiagnosed as pulmonary tuberculosis [4]. The occurrence of ABPA in patients with active pulmonary tuberculosis has been rarely reported. Here we present a rare case of 80 years old male patient in which active pulmonary TB and ABPA were present simultaneously. This was possible only because of use of Cartridge based nucleic acid amplification test (CBNAAT) to rule out active pulmonary TB during ABPA evaluation.