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Epigenetics Changes Nothing: What a New Scientific Field Does and Does Not Mean for Ethics and Social Justice

机译:表观遗传学没有变化:新的科学领域是什么,并不意味着道德和社会正义

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Recently, ethicists have posited that consideration of epigenetic mechanisms presents novel challenges to concepts of justice and equality of opportunity, such as elevating the importance of environments in bioethics and providing a counterpoint to gross genetic determinism. We argue that new findings in epigenetic sciences, including those regarding intergenerational health effects, do not necessitate reconceptualization of theories of justice or the environment. To the contrary, such claims reflect a flawed understanding of epigenetics and its relation to genetics that may unintentionally undermine appeals to social justice. We provide a brief summary of epigenetic sciences, focusing on phenomena central to the current ethical discourse. We identify three fallacious modes of reasoning arising from the emergent literature on the ethical and policy implications of epigenetics, including mischaracterization, undue extrapolation, and exceptionalism. We end by discussing how these issues may work against mobilizing health equity policies and present a more modest claim regarding the value of new epigenetic knowledge to health justice by setting this discourse within the context of known themes in biomedical ethics and health policy.
机译:最近,伦理主义者对表观遗传机制的考虑呈现出对司法概念和机会平等的挑战,例如提高生物伦理中环境的重要性,并对总遗传决定措施提供对比。我们认为,表观遗传科学的新发现,包括关于代际健康影响的人,不需要康复司法理论或环境。相反,这种索赔反映了对外观生物学的有缺陷的理解及其与可能无意破坏对社会正义的遗传学的遗传学的关系。我们提供了表观遗传科学的简要概述,重点是现象核心目前的道德话语。我们确定了三种谬误的推理方式,从外表遗传学的道德和政策影响,包括麻比,过度推断和异常主义。我们通过讨论这些问题如何反对动员卫生股权政策,并在生物医学伦理和卫生政策的知名主题的背景下制定本话题,对新的表观遗传知识的价值更加适度的索赔。

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