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Epigenetics Changes Nothing: What a New Scientific Field Does and Does Not Mean for Ethics and Social Justice

机译:表观遗传学什么都不会改变:一个新的科学领域对伦理和社会正义的意义和意义

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摘要

Recently, ethicists have posited that consideration of epigenetic mechanisms presents novel challenges to concepts of justice and equality of opportunity, such as elevating the importance of environments in bioethics and providing a counterpoint to gross genetic determinism. We argue that new findings in epigenetic sciences, including those regarding intergenerational health effects, do not necessitate reconceptualization of theories of justice or the environment. To the contrary, such claims reflect a flawed understanding of epigenetics and its relation to genetics that may unintentionally undermine appeals to social justice. We provide a brief summary of epigenetic sciences, focusing on phenomena central to the current ethical discourse. We identify three fallacious modes of reasoning arising from the emergent literature on the ethical and policy implications of epigenetics, including mischaracterization, undue extrapolation, and exceptionalism. We end by discussing how these issues may work against mobilizing health equity policies and present a more modest claim regarding the value of new epigenetic knowledge to health justice by setting this discourse within the context of known themes in biomedical ethics and health policy.
机译:最近,伦理学家认为,表观遗传机制的提出给正义和机会均等的概念提出了新的挑战,例如,提高了环境在生物伦理学中的重要性,并为总体遗传决定论提供了对立。我们认为表观遗传学的新发现,包括与代际健康影响有关的发现,并不需要重新构想正义或环境理论。相反,这些主张反映了对表观遗传学及其与遗传学之间关系的错误理解,这可能无意间破坏了对社会正义的诉求。我们提供了表观遗传学的简短摘要,重点介绍了当前道德话语的核心现象。我们从表观遗传学的伦理和政策含义的新兴文献中发现了三种谬误的推理模式,包括错误定性,不适当的推断和例外论。我们首先讨论这些问题如何与动员卫生公平政策相抵触,并通过在生物医学伦理学和卫生政策的已知主题范围内设定这种论述来提出关于新的表观遗传知识对卫生正义的价值的更为谦虚的主张。

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