Reported time to onset of neurological adverse drug reactions among different age and gender groups using metoclopramide: an analysis of the global database VigibaseA (R).

摘要

Despite FDA and EMA warnings of long-term use, little is known regarding the time to onset (TTO) of neurological adverse drug reactions (ADR) for metoclopramide. The aims of this study were, first, to evaluate whether neurological ADRs are more commonly reported for metoclopramide than for other medications, and second, to describe how time to onset of neurological ADRs differs by age and gender.