The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

Scholl Joep H. G.; van Puijenbroek Eugene P.

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The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

机译：发病时间在药物不良反应的统计信号检测中的价值：与荷兰自发报告中的不成比例分析进行比较

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Purpose In pharmacovigilance, the commonly used disproportionality analysis (DPA) in statistical signal detection is known to have its limitations. The aim of this study was to investigate the value of the time to onset (TTO) of ADRs in addition to DPA.

机译：目的在药物警戒中，众所周知，统计信号检测中常用的比例失调分析（DPA）有其局限性。这项研究的目的是研究除DPA之外ADR的起效时间（TTO）的价值。

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《Pharmacoepidemiology and drug safety》 |2016年第12期|共7页
作者
Scholl Joep H. G.; van Puijenbroek Eugene P.;
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正文语种 eng
中图分类药学;
关键词
signal detection; time to onset; latency; pharmacovigilance; ADR; pharmacoepidemiology;

机译：信号检测;发病时间;潜伏期;药物警戒;ADR;药物流行病学;

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1. The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands [J] . Scholl Joep H. G., van Puijenbroek Eugene P. Pharmacoepidemiology and drug safety . 2016,第12期

机译：发病时间在药物不良反应的统计信号检测中的价值：与荷兰自发报告中的不成比例分析进行比较
2. A comparison of measures of disproportionality for signal detection on adverse drug reaction spontaneous reporting database of Guangdong province in China. [J] . Li C, Xia J, Deng J, Pharmacoepidemiology and drug safety . 2008,第6期

机译：中国广东省药品不良反应自发报告数据库信号检测不成比例措施的比较。
3. Data mining spontaneous adverse drug event reports for safety signals in Singapore - a comparison of three different disproportionality measures [J] . Ang Pei San, Chen Zhaojin, Chan Cheng Leng, Expert opinion on drug safety . 2016,第5期

机译：数据挖掘自发性不良药物事件报告，以获取新加坡的安全信号-三种不同失衡措施的比较
4. A Systematic Prediction of Adverse Drug Reactions Using Pre-clinical Drug Characteristics and Spontaneous Reports [C] . Ngufor Che, Wojtusiak Janusz, Pathak Jyotishman IEEE International Conference on Healthcare Informatics . 2015

机译：利用临床前药物特性和自发报告对药物不良反应进行系统的预测
5. Signal Detection of Adverse Drug Reaction using the Adverse Event Reporting System: Literature Review and Novel Methods [D] . Pham, Minh H. 2018

机译：使用不良事件报告系统的不良药物反应的信号检测：文献综述和新方法
6. Suspected Adverse Drug Reactions Related to Breast Cancer Chemotherapy: Disproportionality Analysis of the Brazilian Spontaneous Reporting System [O] . Flávia Campos Barcelos, Guacira Corrêa de Matos, Mario Jorge Sobreira da Silva, -1

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7. Ototoxic Adverse Drug Reactions: A Disproportionality Analysis Using the Italian Spontaneous Reporting Database [O] . Maria Antonietta Barbieri, Giuseppe Cicala, Paola Maria Cutroneo, 2019

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The value of time-to-onset in statistical signal detection of adverse drug reactions: a comparison with disproportionality analysis in spontaneous reports from the Netherlands

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