PSA-stratified detection rates for [Ga-68]THP-PSMA, a novel probe for rapid kit-based Ga-68-labeling and PET imaging, in patients with biochemical recurrence after primary therapy for prostate cancer

摘要

Purpose [Ga-68]Tris(hydroxypyridinone)(THP)-PSMA is a novel radiopharmaceutical for one-step kit-based radiolabelling, based on direct chelation of Ga-68(3+) at low concentration, room temperature and over a wide pH range, using direct elution from a Ge-68/Ga-68-generator. We evaluated the clinical detection rates of [Ga-68]THP-PSMA PET/CT in patients with biochemically recurrent prostate cancer after prostatectomy.