Visible-Light-Promoted Alkylation of Indoles with Tertiary Amines by the Oxidation of a sp(3) C-H Bond

摘要

A visible-light driven reaction for the synthesis of 3-arylmethyl indole derivatives using tertiary amines and indoles was first reported. Corresponding products were obtained with yields of up to 70%, and various functional groups on the indoles were well tolerated when Rose Bengal was used as a photosensitizer and air was used as a green oxidant under mild reaction conditions.