Treatment of methicillin-resistant Staphylococcus aureus surgical site infections.

摘要

It is estimated that there are approximately 500 000 cases of surgical site infec-I tions (SSIs) each year in the United States. Surgical site infection occurs in 2% to 5% of patients who undergo surgical procedures and is associated with serious negative outcomes, including increased health care-associated morbidity and mortality. The risk of mortality increases 2- to 11-fold in patients with SSI. Moreover, the duration of postoperative hospitalization may increase by an average of 7 to 10 days because of an episode of SSI. Another important issue is the burden of increased costs for patients and health care institutions. The estimated cost per patient per SSI has ranged from Dollars 3000 to Dollars 29 000 in published studies. Accordingly, the appropriate and timely management of SSI is of critical importance to prevent serious complications.