Be prudent of ketamine in treating resistant depression in patients with cancer.

摘要

Pain, suffering, hopelessness, loneliness, and fear of death are the main contributing risk factors to the development of depression in patients with cancer. Antidepressants are intended to improve patients' mood status and alleviate depression. Unfortunately, conventional antidepressants, such as imipra-mine and fluoxetine, cannot effectively ameliorate the symptoms of refractory depression in some patients with cancer.