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首页> 外文期刊>Journal of mechanics in medicine and biology >FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS
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FLOW DYNAMIC COMPARISON BETWEEN RECESSED HINGE AND OPEN PIVOT BI-LEAFLET HEART VALVE DESIGNS

机译:后铰链与开放式PIVOT双叶心瓣设计之间的流动动力学比较

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摘要

The flow dynamics through the peripheral and hinge regions of a bi-leaflet mechanical heart valve are complex and result in abnormally high shear stresses particularly during the closing phase of the valve function. It has been observed that the late stages of closure are more significant in the dynamics of platelet activation; therefore, the later stages of closure are simulated by solving the two-dimensional Navier-Stokes equations using an Eulerian Levelset-based sharp interface Cartesian grid method. Using a fixed Cartesian mesh incorporating local mesh refinement for solution accuracy and efficiency, the flow-through within a recessed hinge design and an open pivot hinge design is compared. Platelets are modeled as point particles by Lagrangian particle tracking algorithm with one way coupling. A dilute particle flow is assumed and particle-particle interactions are neglected. It was observed that the hinge region of the open pivot valve indicated a lower potential for activation of platelets compared to that in valves with a recessed hinge design.
机译:通过双叶机械心脏瓣膜的外围和铰链区域的流动动力学非常复杂,特别是在瓣膜功能关闭阶段,会导致异常高的剪切应力。已经观察到,闭合的后期在血小板活化的动力学中更为重要。因此,通过使用基于欧拉水平集的尖锐接口笛卡尔网格方法求解二维Navier-Stokes方程,可以模拟封闭的后期阶段。使用固定的笛卡尔网格并结合局部网格细化以提高解决方案的准确性和效率,比较了嵌入式铰链设计和开放式铰链设计中的流通量。通过单向耦合的拉格朗日粒子跟踪算法将血小板建模为点粒子。假定了稀颗粒流动,而忽略了颗粒间的相互作用。观察到,与具有凹入式铰链设计的阀相比,打开的枢转阀的铰链区域显示出较低的血小板激活潜力。

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