An Efficient One-Pot Three Component Synthesis of 1,2-Dihydro-1-arylnaphtho[1,2-e][1,3]oxazine-3-ones Using Montmorillonite K10 under Solvent Free Conditions

摘要

An efficient green protocol for the preparation of 1,2-dihydro-1-arylnaphtho[1,2-e][1,3]oxazine-3-ones employing a three-component one-pot condensation reaction of b-naphthol, aromatic aldehyde, urea or thiourea in the presence of montmorillonite K10 clay under solvent free conditions has been described. The present procedure offers advantages such as shorter reaction time (<90 min), simple workup, excellent yields, recovery and reusability of catalyst.