Borane Complexes of 2-(1-Methyl-1,2,5,6-tetrahydropyridin-3-yl)benzoxazoles

摘要

2-Pyridin-3-ylbenzoxazoles were synthesized by the reaction between 3-pyridinecarboxaldehyde and substituted o-aminophenols in the presence of iodobenzene diacetate. The resulting benzoxazoles 3 were treated with methyl iodide to give the corresponding pyridinium salts 4 which underwent the hybride reduction with sodium borohydride or sodium cyanoborohydride to produce 2-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)benzoxazole borane complex derivatives.