Comparative investigations of structure and absorptive capacity ofnano- and microsized magnetic-operated particles for their applicationin medicine and biology

摘要

For the first time, the comparative investigations of structure and sorption efficiency of nano- andmicrosized magnetic-operated particles in respect to both the antigen and virus hepatitis B and alsoto the substance-markers (low-, middle- and highmolecular substances) were carried out. Thesorption efficiency of magnetic particles: magnetite (Fe_3O_4), cobalt-ferrite (CoFe_2O_compositeferro-carbon (FeC) to the substances of different molecular weight was evaluated in vitroexperiments. The high absorptive capacity to low- and highmolecular substance-markers has beenobserved for microsized composites of FeC. Absorptive capacity of the nanosized Fe_3O_4andCoFe_2O_4particles to the substance-markers was low. But the nanosized Fe_3O_4and CoFe_had a good absorptive capacity to virus of hepatitis B and its antigen (HBsAg). Thesorption efficiency results of nano- and microsized magnetic particles correlate with the structure oftheir surface.