Paternity in Klinefelter syndrome - another case report.

摘要

I read with interest the article by Selice et al. (1), in which 84 patients with Klinefelter syndrome (47, XXY) were evaluated with seminal analysis. As a result, 8.3% patients had sperm in the ejaculate, although criptozoospermia was noticed. The authors concluded that men with Klinefelter syndrome are not always sterile. This is indeed the case. Some men with non-mosaic 47,XXY produce a small number of sperm, allowing for the use of assisted reproductive techniques with intracytoplasmic sperm insertion (ICSI) to achieve pregnancy (2). There have been very few cases of naturally conceived offspring of proven paternity (3, 4). Here we also reported a subject with Klinefelter syndrome, in whom paternity was confirmed by DNA-fingerprinting analysis.