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Obesity, Oxidative Stress, and Their Effect on Serum Heme Oxygenase-1 Concentrations and Insulin in Children Aged 3 to 5 Years in a Pediatric Hospital of the Ministry of Health CDMX

机译:肥胖,氧化应激及其对卫生部CDMX儿科医院3至5岁儿童血清血红素氧合酶1浓度和胰岛素的影响

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摘要

Background: Obesity during early stages of life may condition states of oxidative stress. Heme oxygenase-1 (HO-1) is an enzyme involved in oxidative metabolism; it has antioxidant and anti-inflammatory functions and is related in sensitivity to insulin. However, a high concentration of this enzyme has been described to cause alterations such as insulin resistance. The objective of this work was to study the relationship between obesity, oxidative stress, HO-1, and insulin in children aged 3 to 5 years.
机译:背景:肥胖在生命的早期阶段可能会调节氧化应激状态。血红素加氧酶-1(HO-1)是一种参与氧化代谢的酶。它具有抗氧化和抗炎功能,并且对胰岛素的敏感性有关。但是,已经描述了这种酶的高浓度会引起诸如胰岛素抵抗的改变。这项工作的目的是研究3至5岁儿童的肥胖,氧化应激,HO-1和胰岛素之间的关系。

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