RADICAL CYCLIZATION USING A THIOACETAL GROUP FOR RADICAL GENERATION

摘要

The generation and cyclization of several heterocyclic radicals were investigated. The hydrogen abstraction from 1,3-dithiane, 1,3-dithiolane, and 1,3-oxathiane rings by a benzophenone triplet generated the corresponding heterocyclic radicals, which gave the cyclized products by intramolecular addition to alpha,beta-unsaturated esters. Diastereoselective radical cyclization using chiral acetals was also investigated. Copyright (C) 1996 Elsevier Science Ltd. [References: 20]