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Biogenic Amine Neurotransmitter Transporters: Just When You Thought You Knew Them

机译:生物胺神经递质转运蛋白:就在您以为知道它们的时候

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摘要

Plasma membrane transporters have long been known to support the reuptake of biogenic amine neurotransmitters following release in the central and peripheral nervous systems. Using high-resolution imaging, patch-clamp and ampero-metric approaches, aswell as molecular manipulations of transporter-regulatory pathways, surprising new details have been uncovered as to how transporters work and are influenced by signaling pathways and psychostimulants.
机译:众所周知,质膜转运蛋白在中枢神经系统和周围神经系统释放后会支持生物胺神经递质的再摄取。使用高分辨率成像,膜片钳和安培测量方法以及转运蛋白调节途径的分子操纵,已发现令人惊奇的新细节,涉及转运蛋白如何工作并受信号传导途径和精神刺激剂影响。

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