Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

Georg Lenz; R. Eric Davis; Vu N. Ngo; Lloyd Lam; Thaddeus C. George; George W. Wright; Sandeep S. Dave; Hong Zhao; Weihong Xu; Andreas Rosenwald; German Ott; Hans Konrad Muller-Hermelink; Randy D. Gascoyne; Joseph M. Connors; Lisa M. Rimsza; Elias Campo

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Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

机译：人弥漫性大B细胞淋巴瘤的致癌性CARD11突变。

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摘要

Diffuse large B cell lymphoma (DLBCL) is the most common form of non-Hodgkin's lymphoma. In the least curable (ABC) subtype of DLBCL, survival of the malignant cells is dependent on constitutive activation of the nuclear factor-KB (NF-kB) signaling pathwa

机译：弥漫性大B细胞淋巴瘤（DLBCL）是非霍奇金淋巴瘤的最常见形式。在DLBCL的最小治愈（ABC）亚型中，恶性细胞的存活取决于核因子-κB（NF-kB）信号通路的组成性激活。

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来源
《Science》 |2008年第5870期|p.1676-1679|共4页
作者
Georg Lenz; R. Eric Davis; Vu N. Ngo; Lloyd Lam; Thaddeus C. George; George W. Wright; Sandeep S. Dave; Hong Zhao; Weihong Xu; Andreas Rosenwald; German Ott; Hans Konrad Muller-Hermelink; Randy D. Gascoyne; Joseph M. Connors; Lisa M. Rimsza; Elias Campo;
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作者单位

Metabolism Branch, Division of Cancer Treatment and Diagnosis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. MYD88, CARD11, and CD79B Oncogenic Mutations are Rare Events in the Indian Cohort of De Novo Nodal Diffuse Larqe B-Cell Lymphoma [J] . Vaishali Aggarwal, Ashim Das, Amanjit Bal, Applied immunohistochemistry and molecular morphology: AIMM . 2019,第4期

机译：MyD88，CARD11和CD79B致癌突变是印度人队列的稀有事件，即Novo Nodal Diffuse Larqe B细胞淋巴瘤
2. MYD88, CD79B, and CARD11 Gene Mutations in CD5-Positive Diffuse Large B-Cell Lymphoma [J] . Takeuchi Toshifumi, Yamaguchi Motoko, Kobayashi Kyoko, Cancer: A Journal of the American Cancer Society . 2017,第7期

机译：CD5阳性弥漫性大B细胞淋巴瘤中的MYD88，CD79B和CARD11基因突变
3. A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma. [J] . Dong G, Chanudet E, Zeng N, Clinical cancer research: an official journal of the American Association for Cancer Research . 2011,第6期

机译：A20，ABIN-1 / 2和CARD11突变及其在胃肠道弥漫性大B细胞淋巴瘤中的预后价值。
4. Mutational profile of Diffuse Large B-cell Lymphoma with central nervous system relapse: analysis of CBioPortal for Cancer Genomics database [C] . Elena Voropaeva, Olga Beresina, Tatyana Pospelova, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：弥漫性大B细胞淋巴瘤与中枢神经系统复发的突变特征：用于癌症基因组学数据库的CBioPortal分析
5. Safety and Efficacy of the Immunomodulatory Drug (IMiD) Lenalidomide in Patients with Lymphoma: Development of RU051417I - Phase I/II Open-Label Study of R-ICE (Rituximab-Ifosfamide-Carboplatin-Etoposide) with Lenalidomide [R2-ICE] in Patients with First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL). [D] . Kasi, Pashtoon Murtaza. 2018

机译：免疫调节药物来那度胺在淋巴瘤患者中的安全性和有效性：RU051417I-R-ICE（利妥昔单抗-异环磷酰胺-卡铂-依托泊苷）与来那度胺[R2-ICE]的I / II期开放标签研究的进展初次复发/原发性难治性弥漫性大B细胞淋巴瘤（DLBCL）。
6. A Quantitative Signaling Screen Identifies CARD11 Mutations in the CARD and LATCH Domains That Induce Bcl10 Ubiquitination and Human Lymphoma Cell Survival [O] . Waipan Chan, Thomas B. Schaffer, Joel L. Pomerantz 2013

机译：定量信号传导筛查可识别可导致Bcl10泛素化和人类淋巴瘤细胞存活的CARD和LATCH域中的CARD11突变。
7. A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma [O] . Zeng, N, Chanudet, E, Dong, G, 2011

机译：a20，aBIN-1/2和CaRD11突变及其在胃肠道弥漫性大B细胞淋巴瘤中的预后价值

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Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

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