The pattern of localization of the putative oocyte activation factor, phospholipase Cζ, in uncapacitated, capacitated, and ionophore-treated human spermatozoa

P. Grasa1? K. Coward12? C. Young1? and J. Parrington13

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The pattern of localization of the putative oocyte activation factor, phospholipase Cζ, in uncapacitated, capacitated, and ionophore-treated human spermatozoa

机译：假定的卵母细胞活化因子，磷脂酶Cζ在未失能，失能和经离子载体处理的人类精子中的定位模式

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BACKGROUND Recent studies suggest that in mammals, oocyte activation at fertilization is triggered by a sperm-specific phospholipase C, PLCζ. We investigated PLCζ localization in human spermatozoa.

机译：背景技术最近的研究表明，在哺乳动物中，受精卵母细胞的活化是由精子特异性磷脂酶CPLCζ触发的。我们调查了人类精子中PLCζ的定位。

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《Human Reproduction》 |2008年第11期|2513-2522|共10页
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P. Grasa1? K. Coward12? C. Young1? and J. Parrington13;
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Department of Pharmacology University of Oxford Mansfield Road Oxford OX1 3QT UK;

Present address: Nuffield Department of Obstetrics and Gynaecology University of Oxford Level 3 Women's Centre John Radcliffe Hospital Headington Oxford OX3 9DU UK;

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1. The pattern of localization of the putative oocyte activation factor, phospholipase Czeta, in uncapacitated, capacitated, and ionophore-treated human spermatozoa. [J] . Grasa P, Coward K, Young C, Human Reproduction . 2008,第11期

机译：假定的卵母细胞活化因子，磷脂酶Czeta在未失能，失能和用离子载体处理的人类精子中的定位模式。
2. Subcellular localization of phospholipase C zeta in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation [J] . Escoffier Jessica, Yassine Sandra, Lee Hoi Chang, Molecular human reproduction. . 2015,第1a2期

机译：磷脂酶C zeta在人精子中的亚细胞定位及其在DPY19L2缺陷型精子中的缺失与其在卵母细胞激活中的作用一致
3. Effect of platelet-activating factor (PAF) on human spermatozoa–oocyte interactions [J] . M. J. Angle, R. Tom, K. Jarvi, Journal of reproduction and fertility . 1993,第2期

机译：血小板活化因子（PAF）对人精子-卵母细胞相互作用的影响
4. 12(S)-HETE PRIMES A PHOSPHOLIPASE D PATHWAY IN ACTIVATED HUMAN BLOOD MONONUCLEAR CELLS [C] . Alexia Zakaroff, Nadia Meskini, Catherine Joulain, International Washington Spring Symposium . 1996

机译：12（s） - 在活化的人体血液单核细胞中，将磷脂酶D途径突出
5. Characterization of the involvement of integrins, focal adhesion kinase, and phospholipase C enzymes endogenous to the oocyte in bovine fertilization and oocyte activation [D] . Sessions, Benjamin Rand 2012

机译：牛受精和卵母细胞活化中卵母细胞内源性整合素，粘着斑激酶和磷脂酶C酶的参与特征
6. Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation [O] . Jessica Escoffier, Sandra Yassine, Hoi Chang Lee, -1

机译：磷脂酶Cζ在人精子中的亚细胞定位及其在DPY19L2缺陷型精子中的缺失与其在卵母细胞激活中的作用一致
7. Timing of oocyte activation, pronucleus formation and cleavage in humans after intracytoplasmic sperm injection (ICSI) with testicular spermatozoa and after ICSI or in-vitro fertilization on sibling oocytes with ejaculated spermatozoa [O] . Z. P. Nagy, C. Janssenswillen, R. Janssens, 1998

机译：卵母细胞活化，原核糖形成和乳糜核糖蛋白酶（ICSI）与睾丸精子和ICSI后的体外施肥后的卵瘤形成和切割的定时，用射精精子伴随卵母细胞

The pattern of localization of the putative oocyte activation factor, phospholipase Cζ, in uncapacitated, capacitated, and ionophore-treated human spermatozoa

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