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Recombinant Human Growth Hormone and Rosiglitazone for Abdominal Fat Accumulation in HIV-Infected Patients with Insulin Resistance: A Randomized Double-Blind Placebo-Controlled Factorial Trial

机译：重组人生长激素和罗格列酮对HIV感染的胰岛素抵抗患者腹部脂肪堆积的影响：一项随机双盲安慰剂对照的析因试验

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BackgroundRecombinant human growth hormone (rhGH) reduces visceral adipose tissue (VAT) volume in HIV-infected patients but can worsen glucose homeostasis and lipoatrophy. We aimed to determine if adding rosiglitazone to rhGH would abrogate the adverse effects of rhGH on insulin sensitivity (SI) and subcutaneous adipose tissue (SAT) volume.

机译：背景重组人生长激素（rhGH）减少了HIV感染患者的内脏脂肪组织（VAT）量，但可能使葡萄糖稳态和脂肪萎缩恶化。我们旨在确定将罗格列酮添加到rhGH中是否可以消除rhGH对胰岛素敏感性（SI）和皮下脂肪组织（SAT）量的不利影响。

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期刊名称 other
作者
Marshall J. Glesby; Jeanine Albu; Ya-Lin Chiu; Kirsis Ham; Ellen Engelson; Qing He; Varalakshmi Muthukrishnan; Henry N. Ginsberg; Daniel Donovan; Jerry Ernst; Martin Lesser; Donald P. Kotler;
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年(卷),期 -1(8),4
年度 -1
页码 e61160
总页数 12
原文格式 PDF
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1. Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension. [J] . Falutz J, Potvin D, Mamputu J JAIDS: Journal of acquired immune deficiency syndromes . 2010,第3期

机译：替沙莫林（一种生长激素释放因子）对受HIV感染的腹部脂肪积聚的患者的影响：一项具有安全性延长的随机安慰剂对照试验。
2. The Effects of Omega-3 Fatty Acids and Vitamin E -Co-Supplementation on Indices of Insulin Resistance and Hormonal Parameters in Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial [J] . Ebrahimi Faraneh Afshar, Samimi Mansooreh, Foroozanfard Fatemeh, Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association . 2017,第6期

机译：ω-3脂肪酸和维生素E-CCO补充对多囊卵巢综合征患者胰岛素抵抗和激素参数的依据的影响：随机，双盲，安慰剂对照试验
3. Randomised, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy. [J] . Osterziel KJ, Strohm O, Schuler J, The Lancet . 1998,第9111期

机译：人类重组生长激素治疗因扩张型心肌病而导致的慢性心力衰竭的随机，双盲，安慰剂对照试验。
4. A Phase I, Double-Blind, Randomized, Dose Escalating Crossover Study ofan Oral Formulation of Human Growth Hormone in Healthy Male Volunteers [C] . Steven M. Dinh, Puchun Liu, Ehud Arbit, Controlled Release Society annual meeting . 2004

机译：健康男性志愿者中人类生长激素口服制剂的I期，双盲，随机，剂量递增交叉研究
5. A Randomized, Double-Blind, Placebo-Controlled Crossover Trial Evaluating the Effect of Intranasal Insulin on Cognition and Emotional Processing in Individuals with Treatment-Resistant Major Depressive Disorder. [D] . Cha, Danielle Soh-Young. 2016

机译：一项随机，双盲，安慰剂对照的交叉试验评估了鼻内胰岛素对难治性重度抑郁症患者认知和情绪加工的影响。
6. Vitamin B12 in HIV-Infected Patients with Insulin Resistance and Visceral Adiposity in a Randomized Trial of Recombinant Human Growth Hormone and Rosiglitazone (OR12-05-19) [O] . Heather Guetterman, Bryan Gannon, Saurabh Mehta, 2019

机译：重组人生长激素和罗格列酮随机试验中HIV感染和胰岛素抵抗和内脏肥胖患者的维生素B12（OR12-05-19）
7. Recombinant human growth hormone and rosiglitazone for abdominal fat accumulation in HIV-infected patients with insulin resistance: a randomized, double-blind, placebo-controlled, factorial trial. [O] . Marshall J Glesby, Jeanine Albu, Ya-Lin Chiu, 2013

机译：重组人生长激素和罗格列酮用于HIV感染的胰岛素抵抗患者的腹部脂肪积累：一项随机，双盲，安慰剂对照的因子试验。

Recombinant Human Growth Hormone and Rosiglitazone for Abdominal Fat Accumulation in HIV-Infected Patients with Insulin Resistance: A Randomized Double-Blind Placebo-Controlled Factorial Trial

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